Gastric pitsThe gastric glands open into the bottom of each pit.
MucosaThe layer that makes the gastric juice.
Gastric glandsTheir cells make acid, enzymes, mucus and hormones.
Muscularis mucosaePart of the mucosa, not the main muscle wall.
SubmucosaConnective tissue with blood and lymph vessels.
Oblique layerOnly the stomach has this third layer; it helps churn the food.
Circular layerIts fibres run round the stomach.
Longitudinal layerIts fibres run the length of the stomach.
SerosaThe outermost layer of the stomach wall.
The cells of a gastric gland 4
Mucous neck cellsThey make a thin, acidic mucus.
Parietal cellsThey make hydrochloric acid and intrinsic factor.
Chief cellsThey make pepsinogen, which acid turns into pepsin.
Enteroendocrine cellsThey make hormones; G cells make gastrin.
How this list was compiled: Every name and detail checked on 2026-09-29 against OpenStax Anatomy and Physiology 2e, section 23.4 The Stomach (rugae, gastric pits and glands, mucous neck cells, parietal cells making hydrochloric acid and intrinsic factor, chief cells making pepsinogen, enteroendocrine cells and gastrin, the extra inner oblique muscle layer), https://openstax.org/books/anatomy-and-physiology-2e/pages/23-4-the-stomach, and section 23.1 (mucosa, muscularis mucosae, submucosa, muscularis, serosa), https://openstax.org/books/anatomy-and-physiology-2e/pages/23-1-overview-of-the-digestive-system; and against Wikipedia, text only: Stomach and Gastric glands. Licence: own work
The drawing: Drawn for this site on 2026-09-29 from plain geometry; nothing traced. Licence: own work
How it works
The top drawing is a block cut from the stomach wall, from the folded lining to the outer covering. The bottom one enlarges a single gastric pit and its gland, with the cells that make the gastric juice.
Read the full guide
The wall, then one gland
Numbers 1 to 10 are the wall: a fold of the lining, the pits and glands in it, the thin muscle under it, the submucosa, the three muscle layers and the serosa. Numbers 11 to 14 are the cells of one gland, from the neck down to the base. Each kind sits in its own zone, so the position in the gland tells you which cell it is.
The stomach has three muscle layers, not two: the extra oblique layer inside helps it churn food.
Questions and answers
What is a gastric pit?
A small dip in the stomach's lining. The gastric glands open into the bottom of each pit, and their juice flows up through it into the stomach.
What do parietal and chief cells make?
Parietal cells make hydrochloric acid and intrinsic factor. Chief cells make pepsinogen, which the acid turns into the protein-digesting enzyme pepsin.
What are the layers of the stomach wall?
From the inside out: the mucosa with its pits and glands, the submucosa, the muscularis with its oblique, circular and longitudinal layers, and the serosa.