How it works
Before birth the brain starts as the front end of a hollow tube. Two drawings of the developing brain show it from the side, first with three swellings and then with five.
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Three vesicles first
Rings 1 to 3 are the primary vesicles from front to back: the forebrain or prosencephalon, the midbrain or mesencephalon and the hindbrain or rhombencephalon. Ring 4 is the narrow tube behind them, the spinal cord.
Then five, on a bent tube
The forebrain has divided into the telencephalon and the diencephalon, and the hindbrain into the metencephalon and the myelencephalon. The midbrain stays one piece at the top of the arch. Each curved arrow marks a bend: the cephalic flexure under the midbrain, the pontine flexure behind it and the cervical flexure beside the spinal cord.
- Front to back the five run telencephalon, diencephalon, mesencephalon, metencephalon, myelencephalon.
- Only the first and the last primary vesicle divide; the middle one does not.
Questions and answers
What are the three primary brain vesicles?
The prosencephalon or forebrain, the mesencephalon or midbrain and the rhombencephalon or hindbrain. They are three swellings at the front end of the neural tube, and the hindbrain runs on into the spinal cord.
What are the five secondary brain vesicles?
The telencephalon and diencephalon, which come from the forebrain; the mesencephalon; and the metencephalon and myelencephalon, which come from the hindbrain. Sources put three vesicles at about the fourth week of development and five in the fifth.
What does each brain vesicle become?
The telencephalon becomes the cerebrum. The thalamus forms from the diencephalon. The mesencephalon stays the midbrain. The metencephalon turns into pons and cerebellum; the myelencephalon turns into the medulla oblongata.
Is this the figure for "label the following picture of a developing brain"?
No. That line comes from a publisher's homework set, and its picture is theirs. These two drawings are our own and show the same vesicles, so you can practice the names here. We have no answer key for any homework set.