Phospholipid bilayerTwo layers of phospholipids, the main fabric of the membrane. Tails face in and heads face out.
Hydrophilic headThe water-loving head of a phospholipid, a phosphate group on glycerol. Heads face the water on both sides.
Hydrophobic tailsTwo fatty acid chains that avoid water. So they face each other in the core of the membrane.
Integral proteinA protein built right into the membrane. Its water-avoiding middle is held in the bilayer's core.
Channel proteinA protein with a passage that lets specific ions or water through. Some are always open, others are gated.
GlycoproteinA protein with a carbohydrate chain attached, facing outside. It helps cells recognise each other.
Lipids: 4 1
CholesterolA lipid of four fused carbon rings. It sits alongside the phospholipids in the membrane's core.
Proteins: 5 2
Carrier proteinA protein that binds a substance and helps it across the membrane.
Peripheral proteinA protein on one face of the membrane, not built in. It is attached to an integral protein or to phospholipids.
Around the membrane: 4 4
GlycolipidA lipid with a carbohydrate chain attached, on the outer face only.
Cytoskeleton filamentsProtein fibres inside the cell. Membrane proteins can serve as their attachment points.
Extracellular fluid (outside the cell)The fluid outside the cell. Carbohydrate chains face this side only.
Cytoplasm (inside the cell)The inside of the cell, where the cytoskeleton and peripheral proteins sit.
How this list was compiled: Read 2026-09-26. OpenStax Biology 2e, section 5.1 Components and Structure, https://openstax.org/books/biology-2e/pages/5-1-components-and-structure : the fluid mosaic model of phospholipids, cholesterol, proteins and carbohydrates; a phospholipid as glycerol, two fatty acids and a phosphate-linked head; hydrophilic heads facing out and hydrophobic tails facing each other in a lipid bilayer; cholesterol of four fused carbon rings alongside the phospholipids in the core; integral proteins integrated into the membrane with hydrophobic membrane-spanning regions; peripheral proteins on the exterior and interior surfaces attached to integral proteins or phospholipids, serving as enzymes, cytoskeleton attachments or recognition sites; carbohydrates only on the exterior surface, forming glycoproteins and glycolipids, together the glycocalyx, used in cell recognition. Section 5.2 Passive Transport, https://openstax.org/books/biology-2e/pages/5-2-passive-transport : channel proteins, specific, open at all times or gated, aquaporins passing water; carrier proteins binding a substance and aiding its diffusion. Licence: own work
The drawing: Drawn for this site by script, 2026-09-26. Own work, nothing traced. Licence: own work
How it works
A cell membrane labeled diagram of the fluid mosaic model: the phospholipid bilayer, the proteins built into and stuck onto it, and the sugar chains on its outer face. Start with the 6 main parts.
Read the full guide
Parts of a phospholipid
Each phospholipid has a water-loving head and two water-avoiding fatty acid tails. In water they form two layers with the tails inside and the heads facing out on both sides: the bilayer. Cholesterol sits among the tails.
Types of membrane proteins
Integral proteins are built through the bilayer; channel and carrier proteins are kinds that move substances across it. Peripheral proteins sit on one face. A glycoprotein carries a sugar chain on the outside, like a glycolipid.
Sugar chains point outward only: if a bead chain is on a molecule, you are looking at the outside of the cell.
Questions and answers
Why is it called the fluid mosaic model?
Because the membrane is a mosaic of phospholipids, cholesterol, proteins and carbohydrates that together give it a fluid character.
What is the difference between integral and peripheral proteins?
Integral proteins are built into the membrane, their middle held in the bilayer's core. Peripheral proteins sit on one face, attached to integral proteins or phospholipids.
What does a channel protein do?
It forms a passage that lets specific ions or water across the membrane. Some channels are always open; others are gated and open only when signalled.