How it works
A human skin cell diagram at the scale of single cells. It shows the epidermis of thick skin, from the dermis up to the flakes at the surface.
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The layers, bottom to top
New cells form in the stratum basale, one row sitting on the basement membrane. Pushed upward, they join the stratum spinosum, where desmosomes hold them together. In the stratum granulosum they flatten and fill with keratohyalin granules. The stratum lucidum is a thin clear layer seen only in thick skin, on the palms and soles. The stratum corneum is sheet upon sheet of flat dead cells.
A Langerhans cells diagram, and two more cells
Most cells here are keratinocytes. Three others live among them. The melanocyte, in the bottom row, makes pigment. The Langerhans cell, among the spiny cells, belongs to the immune system. The Merkel cell, in the bottom row beside a nerve ending, senses light touch.
- The layers are the brackets on the left; tap a bracket, not a cell, for a layer.
- The quiz accepts stratum germinativum for the stratum basale.
Questions and answers
What are the layers of the epidermis in order?
From the deepest to the surface: stratum basale, stratum spinosum, stratum granulosum, stratum lucidum and stratum corneum. The stratum lucidum is seen only in thick skin, so thin skin shows four.
What are the four cells of the epidermis?
Keratinocytes, melanocytes, Langerhans cells and Merkel cells. Keratinocytes make up about nine cells in ten.
How do I label the structures of integument in the epidermis?
Start at the bottom. The single row of tall cells is the stratum basale, and each layer above it has its own look: spiny, grainy, clear, then flat and dead. This drawing is our own, not a copy of a course figure.
What holds the cells of the epidermis together?
Desmosomes, small junctions that fasten one keratinocyte to the next. They are the spines of the stratum spinosum. The round inset enlarges one.