How it works
A ribosome diagram labeled in two views: one ribosome building a protein, then where ribosomes sit in a cell. Start with the 5 main parts.
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One ribosome
A ribosome has two parts, a large and a small subunit, each built from ribosomal RNA and proteins. The mRNA runs between them; tRNAs bring amino acids, and the polypeptide chain grows out of the top.
In the cell
Ribosomes are made in the nucleolus. Free ribosomes float in the cytoplasm; bound ribosomes sit on the rough ER. Several can read one mRNA at once, as a polysome.
- Several ribosomes can read the same mRNA at once, each making its own copy of the protein: that string is a polysome.
Questions and answers
What are the two parts of a ribosome?
The large subunit and the small subunit. Each is made of ribosomal RNA and many proteins, and they clamp together round an mRNA to build a protein.
What is the difference between free and bound ribosomes?
Free ribosomes float in the cytoplasm and make proteins used inside the cell. Bound ribosomes sit on the rough endoplasmic reticulum.
Where are ribosomes made?
In eukaryotic cells, their RNA is made and the subunits are put together partly in the nucleolus, inside the nucleus.