• 14 parts
  • Checked October 2026

Bacterial Cell Wall Structure Diagram

Three bacterial cell walls in section: Gram-positive, Gram-negative and acid-fast.

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Each numbered ring is a button. Use the arrow keys to move between them and Enter to choose. Names are read out in Study, and once a part is answered.

All 14 parts on the diagram

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Gram-positive wall 4

  1. Peptidoglycan A thick mesh of sugar chains and short peptides. It makes up most of this wall.
  2. Teichoic acid A long chain bound to the peptidoglycan. It runs through the wall and out past the surface.
  3. Lipoteichoic acid A teichoic acid held in the plasma membrane by a lipid. It crosses the whole wall.
  4. Plasma membrane The membrane under the wall. It encloses the cytoplasm.

Gram-negative wall 6

  1. Outer membrane A second membrane outside the thin peptidoglycan layer. Chains of lipopolysaccharide stand on it.
  2. Lipopolysaccharide Chains of sugars on a lipid anchor in the outer membrane. The lipid part is called lipid A, or endotoxin.
  3. Porin A protein channel through the outer membrane. Small molecules pass through it.
  4. Peptidoglycan Only a thin layer here. It lies in the periplasm between the two membranes.
  5. Periplasm The gel-filled space between the outer membrane and the plasma membrane.
  6. Plasma membrane The inner of the two membranes. It encloses the cytoplasm.

Acid-fast wall 4

  1. Mycolic acids Long fatty acids packed into a waxy outer layer. They make up most of this wall.
  2. Arabinogalactan Branched chains of two sugars. They link the peptidoglycan below to the mycolic acids above.
  3. Peptidoglycan A thin inner layer. The arabinogalactan is linked to it.
  4. Plasma membrane The membrane under the wall. It encloses the cytoplasm.

How this list was compiled: Every part was checked on 2026-10-01 and kept only where two independent sources name it. (1) Gary Kaiser, Microbiology, sections 2.3A The Gram-Positive Cell Wall, 2.3B The Gram-Negative Cell Wall and 2.3C The Acid-Fast Cell Wall, an open college textbook, https://bio.libretexts.org/Bookshelves/Microbiology/Microbiology_(Kaiser)/Unit_1%3A_Introduction_to_Microbiology_and_Prokaryotic_Cell_Anatomy/2%3A_The_Prokaryotic_Cell_-_Bacteria/2.3%3A_The_Peptidoglycan_Cell_Wall/2.3A%3A_The_Gram-Positive_Cell_Wall . (2) Wikipedia, text only: Gram-positive bacteria, https://en.wikipedia.org/wiki/Gram-positive_bacteria ; Gram-negative bacteria; Bacterial cell structure; Teichoic acid; Lipopolysaccharide; Peptidoglycan; Mycobacterium; Mycolic acid. Licence: own work

The drawing: Drawn for this site on 2026-10-01 from plain geometry; nothing traced. Licence: own work

How it works

Each drawing is a slice through the edge of a bacterium, with the outside at the top and the plasma membrane near the bottom. All three walls hold peptidoglycan. What differs is how much, and what lies outside it.

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Thick wall or two membranes

A Gram-positive wall is mostly peptidoglycan, with teichoic acids threaded through it. A Gram-negative wall has only a thin layer, and outside it a second membrane that carries porins and lipopolysaccharide.

The acid-fast wall

Here the thin peptidoglycan is linked to arabinogalactan, and that to a tall layer of mycolic acids. Mycolic acids are long fatty acids, so the outside of this wall is waxy.

  • A teichoic acid stops in the peptidoglycan; a lipoteichoic acid reaches down into the membrane.

Questions and answers

What is the difference between a Gram-positive and a Gram-negative cell wall?

A Gram-positive wall has a thick layer of peptidoglycan with teichoic acids and no outer membrane. A Gram-negative wall has a thin layer of peptidoglycan lying between two membranes, and its outer membrane carries lipopolysaccharide.

Where are endotoxins on a bacterial cell diagram?

In the Gram-negative wall's outer membrane. Endotoxin is another name for lipopolysaccharide, and more exactly for lipid A, the part that anchors each chain in the membrane.

What is an acid-fast cell wall made of?

From the inside out: a thin layer of peptidoglycan, a layer of arabinogalactan linked to it, and an outer layer of mycolic acids. The mycolic acids make up most of the wall.

Why are the walls called Gram-positive and Gram-negative?

The names come from the Gram stain. A thick layer of peptidoglycan holds the stain, so the cell tests positive. A thin layer does not hold it, so the cell tests negative.