Human Body Systems Crossword Puzzle

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Human Body Systems Crossword

Read each clue and write the answer in the squares that start at its number, one letter in each square.

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Tap a square, and its clue shows here.

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Word bank

  • Alveoli
  • Capillary
  • Digestive
  • Endocrine
  • Muscular
  • Oxygen
  • Skeletal
  • Tendon
  • Thymus
  • Urinary

Type in a square and the next one takes over. Tap the same square again, or press Space, to switch between Across and Down. Arrow keys move around the grid, Enter goes to the next clue, and a clue takes you to its squares.

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Answer key: Human Body Systems Crossword

1OX2THYMUSYE3SGNK4ENDO5CRINENOAL6ANPEL7DIGESTIVELAE8MUSCULARLOAL9URINARYIY

Across 2 THYMUS · 4 ENDOCRINE · 7 DIGESTIVE · 8 MUSCULAR · 9 URINARY

Down 1 OXYGEN · 2 TENDON · 3 SKELETAL · 5 CAPILLARY · 6 ALVEOLI

Next step Next: sort organs into their systems

All 48 clues

Show all clues and answers

The Eleven Systems 11

  • Cardiovascular The circulatory system: the pump and the vessels that move blood
  • Digestive System that breaks food down so it can be absorbed
  • Endocrine Glands that send chemical messages through the blood
  • Integumentary Skin, hair and nails: the body's outer covering
  • Lymphatic System that returns fluid to the blood and helps fight germs
  • Muscular System that moves the body by pulling on bones
  • Nervous System of nerve cells that carries signals around the body
  • Reproductive System that makes babies possible
  • Respiratory System that brings air in and breathes carbon dioxide out
  • Skeletal System of 206 bones in an adult that holds the body up
  • Urinary System that filters waste out of the blood and passes it out as liquid

Organs and Tissues 23

  • Alveoli Tiny air sacs at the ends of the smallest airways
  • Artery Thick-walled vessel that carries blood away from the body's pump
  • Bladder Stretchy sac that holds liquid waste until it is time to empty it
  • Brain Control center of the body, protected by the skull
  • Capillary Tiniest blood vessel, with a wall one cell thick
  • Cartilage Firm, bendy tissue in the nose, the ear and the ends of bones
  • Diaphragm Dome-shaped muscle under the chest that pulls air in when it tightens
  • Esophagus Tube that carries swallowed food down from the throat
  • Heart Four-chambered pump at the center of the circulatory system
  • Kidney Bean-shaped organ that filters the blood
  • Ligament Strong band that joins one bone to another at a joint
  • Liver Large organ under the right ribs that makes bile
  • Lungs Pair of spongy breathing organs in the chest
  • Pancreas Gland near the small intestine that makes food-dissolving juices and helps control blood sugar
  • Spinal cord Bundle of nerves running down inside the backbone
  • Spleen Organ on the upper left of the belly that filters the blood
  • Stomach Stretchy bag where food is churned with acid
  • Tendon Tough cord that joins a muscle to a bone
  • Thymus Gland in the chest where T cells mature
  • Thyroid Butterfly-shaped gland in the front of the neck
  • Trachea The windpipe, running from the throat down into the chest
  • Ureter One of two thin tubes that drain the blood filters into the sac below
  • Vein Vessel with valves that carries blood back toward the body's pump

How the Body Works 14

  • Circulation Movement of blood all around the body
  • Enzyme Protein that speeds up a reaction, such as breaking down food
  • Hemoglobin Iron-rich protein that makes red blood cells red
  • Homeostasis Keeping conditions inside the body steady
  • Hormone Chemical messenger carried by the blood
  • Immunity The body's protection against germs
  • Insulin Messenger chemical that lowers the level of sugar in the blood
  • Marrow Soft tissue inside bones where blood cells are made
  • Neuron Another name for a nerve cell
  • Nutrient Useful substance from food that the body absorbs
  • Oxygen Gas we breathe in that every cell needs
  • Plasma Pale yellow liquid part of blood
  • Reflex Fast automatic reaction, like pulling a hand from something hot
  • Urine Liquid waste made by the kidneys

How this list was compiled: 48 clues written for this site in three sets: the eleven organ systems clued by their job, organs and tissues clued by what they do, and the words for how the body works. Facts were checked against Wikipedia's articles on each organ system and organ. Classroom anatomy only: no illness, symptom or treatment is clued. No clue was copied from a published puzzle. Licence: own work

How it works

This human body systems crossword puzzle draws from 48 clues: the eleven organ systems by what they do, the organs and tissues inside them, and the words for how the body works. New puzzle deals a fresh grid.

Read the full guide

Three sets

The Eleven Systems clues each system by its job, from Integumentary to Reproductive. Organs and Tissues runs from Heart to Cartilage. How the Body Works covers words such as Homeostasis, Hormone and Reflex. All mixes them.

Print or solve

Print gives a sheet with the answer key last. To solve on screen, tap a square and type. Untick the word bank in More options for a harder grid.

  • Start with The Eleven Systems: once the system names are in, the organ clues make more sense.
  • No clue prints another answer, so every word in a grid has to come from what you know.

Questions and answers

Is there a body systems crossword with answers?

Yes. Every print ends with the answer key, and Show all clues and answers, under the puzzle, lists all 48 clues with their answers.

Which grades is this body systems crossword puzzle for?

The Eleven Systems suits grades 5 to 8. Organs and Tissues and How the Body Works suit middle school and high school biology, where words such as Homeostasis and Hemoglobin come up. These bands are our judgement, not a published standard.

Why eleven systems?

Most school biology counts eleven: integumentary, skeletal, muscular, nervous, endocrine, cardiovascular, lymphatic, respiratory, digestive, urinary and reproductive. Some books join the immune and lymphatic systems or split out an excretory system, so your list may differ slightly.

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