How it works
The graph follows the voltage across a nerve cell membrane through one impulse, phase by phase. The second drawing shows the action potential at the cell membrane: two channels, the ions that cross, and the pump.
Read the full guide
Read the graph from left to right
Number 1 is the resting potential, the flat line. The stimulus, 2, pushes the voltage up to the threshold, 3, the dashed line. Then the curve rises, 4, depolarization; reaches its peak, 5; and falls, 6, repolarization. It dips below rest, 7, hyperpolarization. The bar under the axis, 8, is the refractory period. On the membrane, sodium ions, 10, come in through their channel, 9. Potassium ions, 12, go out through theirs, 11. The pump is 13.
- Sodium in makes the rise and potassium out makes the fall, so match each channel to its half of the peak.
- Depolarization and repolarization are the two bands under the peak; hyperpolarization is the dip after them.
Questions and answers
What are the phases of an action potential?
The rising phase (depolarization), the peak, the falling phase (repolarization), the undershoot (hyperpolarization) and the refractory period, which overlaps the others. Before and after them the membrane sits at its resting potential.
What happens at the threshold?
If a stimulus lifts the voltage to the threshold, sodium channels open and an action potential starts. A stronger stimulus does not make the impulse bigger, and one that stays under the threshold starts none.
Which ions move during an action potential?
Sodium ions flow into the cell through voltage-gated sodium channels and make the rise. Potassium ions flow out through voltage-gated potassium channels and make the fall. The sodium-potassium pump keeps sodium low and potassium high inside the cell.
What voltage is the resting potential?
It differs from cell to cell. One of this page's sources uses -70 millivolts and the other -60. Both put the peak at about +40, so that is the one figure printed on the graph.
Is this the answer key to "label the diagram modeling the formation of a membrane potential"?
No. That sentence is the title of a publisher's homework activity. This is our own drawing of the same subject: the membrane view shows the channels, the ions and the pump.